| NCT05700942 | AMPLIFY Study: Transcutaneous Spinal Direct Current Stimulation to Enhance Locomotor Rehabilitation After SCI | University of Florida | | - Age 18 - 65 yrs
- Level C1-T12
AIS C, D- ≥ 1 years
- be able to walk 3 meters with or without devices, braces, or assistance of one person
- NOT have diagnosis of other neurologic condition
| Active | 30 | NA | Technology | Standing/walking/mobility | - 10 Meter Walking Test (10 MWT)
- 6-Minute Walk Test (6MWT)
- H reflex
| 8 weeks | 10 March 2023 | 26 January 2023 | 1 | |
| NCT03567213 | Investigation on the Cortical Communication (CortiCom) System | Johns Hopkins University | Single Group Assignment | - Age 22 - 70 yrs
- Level C1-C8
AIS A, B, C, D- ≥ 1 years
- NOT have implanted devices incompatible with MRI
| Recruiting | 3 | Not Applicable | Surgery | General health | | 26 weeks | 14 December 2021 | 25 June 2018 | 1 | |
| NCT05622994 | Effects of CB1 Antagonist/Reverse Agonist Rimonabant on Walking Abilities in Incomplete Spinal Cord Injury | Hospital Nacional de Parapléjicos de Toledo | | - Age 18 - 75 yrs
- Level C4-L1
AIS C, D- ≥ 1 years
- NOT have severe bone, kidney, or liver dysfunction
- NOT have hypothyroidism
| | 80 | PHASE2 | Drug | General health | - 10 Meter Walking Test (10 MWT)
- 6-Minute Walk Test (6MWT)
- Ashworth and Modified Ashworth Scale (MAS)
- European Quality of Life Five Dimension Five Level Scale (EQ-5D-5L)
- Fatigue Severity Scale (FSS)
- Hospital Anxiety and Depression Scale (HADS)
- Numeric Pain Rating Scale
- Penn Spasm Frequency Scale (PSFS)
- Spinal Cord Independence Measure (SCIM)
| 120 days | 01 November 2022 | 21 November 2022 | 1 | |
| NCT05757830 | PURO - PUlmonary Rehabilitation With O-RAGT Platform | Fondazione Don Carlo Gnocchi ETS | | - Age 18 - 90 yrs
- Level T2-S5
AIS B, C, D- All
- Able to use a walker.
| Ended | 20 | NA | Technology | Standing/walking/mobility | | 48 hours | 23 December 2022 | 07 March 2023 | 4 | |
| NCT05646810 | Impact of Peripheral Afferent Input on Central Neuropathic Pain | University of Aarhus | | - Age 18 - 80 yrs
- Level C1-T12
AIS A, B, C, D- ≥ 1 years
| | 20 | NA | Drug | Pain | - Numeric Pain Rating Scale
| 95 minutes | 01 December 2022 | 12 December 2022 | 0 | |
| NCT05705453 | Epidural Stimulation After Neurologic Damage: Long-Term Outcomes | University of Minnesota | | - Age ≥ 22 yrs
- Level C5-S5
AIS A, B- ≥ 1 years
- HAVE an existing and functional implanted spinal cord stimulator system that is FDA approved
- NOT have current or anticipated need for opioid pain medication preventing participation in the rehabilitation program
- NOT have received Botox injections in the last six months
| Recruiting | 50 | NA | Technology | Arm/hand function | - Surface Electromyography (sEMG)
| 10 years | 11 May 2023 | 30 January 2023 | 1 | |
