About this trial

The trial is enrolling individuals with spinal cord injury or other neurological diseases, with moderate to severe walking impairment, to test the effect of wearing a powered external robot device (exoskeleton) on metabolic consumption, heart rate and breathing effort, and fatiguability, compared to conventional walking training. If included, all participants will be trained under three experimental conditions: 1) without exoskeleton; 2) with exoskeleton; and 3) with exoskeleton and walker. Under each condition, participants will sit, stand, walk comfortably with various levels of assistance, walk fast, and complete a sit-to-stand test. Measurements will include a four-minute walking test, a one-minute sit to stand test, metabolic and cardiovascular measurements, and a questionnaire assessment of perceived exertion and user satisfaction. Final assessment with be made at 48 hours after training.