| NCT05462925 | Prediction of Muscle Responsiveness to FES Therapy | University Health Network, Toronto | | - Age ≥ 18 yrs
- Level C1-C8
AIS - ≥ 6 months
- tolerate being in a seated position for at least one hour
- NOT have previous history of any other neuromuscular disorder or conditions that may affect motor response
| Ended | 10 | NA | Technology | Arm/hand function | - Manual Muscle Test (MMT)
- Surface Electromyography (sEMG)
| 30 sessions are completed (6-10 weeks) | 20 July 2022 | 18 July 2022 | 1 | |
| NCT05447676 | Effects of 4-AP on Functional SCI Recovery | Shirley Ryan AbilityLab | | - Age 18 - 85 yrs
- Level C1-L2
AIS A, B, C, D- ≥ 4 weeks
- NO history of renal impairment
- NO debilitating disease prior to the SCI that caused exercise intolerance
- NO history of head injury or stroke
- NO history of seizure or epilepsy
- NO scalp shrapnel, cochlear implants, or aneurysm clips
- NO metal plate in skull
| | 44 | EARLY_PHASE1 | Drug | Standing/walking/mobility | - 10 Meter Walking Test (10 MWT)
- 6-Minute Walk Test (6MWT)
- American Spinal Injury Association Impairment Scale (AIS): International Standards for Neurological Classification of Spinal Cord Injury (ISNCSCI)
- Magnetic Resonance Imaging (MRI) - conventional/anatomical and quantitative
- Manual Muscle Test (MMT)
- Motor evoked potential
- SCI- QOL Bladder Management Difficulties
- SCI-QOL Bowel Management Difficulties
- Surface Electromyography (sEMG)
| 12 weeks | 30 June 2022 | 07 July 2022 | 1 | |
| NCT05433064 | Spinal Cord Stimulation for Spinal Cord Injury Patients - Regain Walk and Alleviate Pain | Buddhist Tzu Chi General Hospital | | - Age 20 - 70 yrs
- Level -
AIS A, B, C, D- ≥ 1 years
- MUST be planning to receive an epidural electrical stimulator
| Recruiting | 12 | NA | Technology | Standing/walking/mobility | - 10 Meter Walking Test (10 MWT)
- American Spinal Injury Association Impairment Scale (AIS): International Standards for Neurological Classification of Spinal Cord Injury (ISNCSCI)
- Ashworth and Modified Ashworth Scale (MAS)
- Berg Balance Scale (BBS)
- Timed Up and Go Test (TUG)
- World Health Organization Quality of Life- BREF (WHOQOL-BREF)
| 25 months | 01 May 2020 | 27 June 2022 | 1 | |
| NCT05425238 | Blood Flow Restriction Resistance Exercise in Lower Cervical Spinal Cord Injury Patients | Riphah International University | | - Age 15 - 50 yrs
- Level C6-C8
AIS A, B- All
- NO other neurologic conditions
| Ended | 16 | NA | Rehabilitation | Arm/hand function | - Ashworth and Modified Ashworth Scale (MAS)
- Hand-Held Myometery / Dynamometry
- Quadriplegia Index of Function-Short Form (QIF-SF)
| 6 weeks | 15 May 2022 | 21 June 2022 | 1 | |
| NCT05467215 | Can Brief Exposure to Hyperoxia Improve Function After Chronic Spinal Cord Injury? | University of Alberta | | - Age 18 - 65 yrs
- Level C5-T10
AIS A, B, C- ≥ 3 months
- NOT have frequent uncontrolled autonomic dysreflexia
- NOT have a cardiac or cardiovascular disease
| Recruiting | 25 | EARLY_PHASE1 | Drug | Sensory function | - Surface Electromyography (sEMG)
| 7 weeks | 11 July 2022 | 20 July 2022 | 1 | |
| NCT05262816 | Effect of Electroacupuncture at Different Acupoints on Bladder Function After Spinal Cord Injury | Second Affiliated Hospital of Wenzhou Medical University | | - Age 18 - 80 yrs
- Level C1-L5
AIS - All
- have passed the period of spinal shock
- have voiding dysfunction after SCI
| | 34 | NA | Psychosocial/other | Bladder health/function | - Electromyography
- Surface Electromyography (sEMG)
| | 20 August 2021 | 02 March 2022 | 1 | |
