| NCT04949763 | Reliability and Validity of the ISNCSCI in Patients With Non-traumatic Spinal Cord Lesions | LIFE - Research and Care Institute - Santa Lucia IRCCS | | - Age ≥ 18 yrs
- Level C1-S5
AIS A, B, C, D- ≤ 6 months
| Ended | 140 | | | General health | | | 01 January 2017 | 02 July 2021 | 0 | |
| NCT04951297 | Development and Validation of a Bowel-routine-based Self Report Questionnaire for Sacral Sparing After Spinal Cord Injury | Peking University Third Hospital | | - Age ≥ 0 yrs
- Level C1-S5
AIS A, B, C, D- ≥ 0 hours
| Ended | 102 | | | Bowel health | | | 01 January 2013 | 06 July 2021 | 0 | |
| NCT04967274 | Reticulospinal Control of Movements | University of Zurich | | - Age 18 - 80 yrs
- Level C4-T12
AIS A, B, C, D- ≤ 80 years
| Recruiting | 248 | NA | Rehabilitation | Standing/walking/mobility | | | 15 January 2022 | 19 July 2021 | 1 | |
| NCT04971408 | Impact of Passive Heat on Metabolic, Inflammatory and Vascular Health in Persons With Spinal Cord Injury | VA Office of Research and Development | | - Age 18 - 60 yrs
- Level C1-S5
AIS A, B, C, D- 1 years - 60 years
| Ended | 10 | NA | Rehabilitation | General health | | | 01 July 2022 | 21 July 2021 | 1 | |
| NCT04041063 | Rehabilitation and Cortical Remodeling After Surgical Intervention for Spinal Cord Injury | Burke Medical Research Institute | | - Age 18 - 50 yrs
- Level C5-C7
AIS A, B, C, D- 6 months - 50 years
- have a C5, C6, or C7 level spinal cord injury for at least 6 months and have some motor dysfunction in the hand.
- have function in the “donor” nerve to be used in the nerve transfer surgery (usually a nerve innervated by a spinal cord segment above the spinal cord injury level).
- have one of the following ASIA impairment scale (AIS):
- AIS A: complete; no feeling or movement below the injury
- AIS B: incomplete; have some feeling, but no movement, below the injury
- AIS C: incomplete; at least some feeling and mostly weak movement below the injury
- AIS D: incomplete; at least some feeling and, some weak but mostly stronger movement below the injury)
- be between the ages of 18 and 50 years
- NOT have a history of seizures, presence of surgically implanted foreign bodies such as a pacemaker, metal plate in the skull, and metal inside the skull.
| Active | 6 | PHASE2 | Technology | Arm/hand function | - Spinal Cord Independence Measure (SCIM)
| | 26 July 2019 | 01 August 2019 | 1 | |
| NCT05095454 | Short-Term Transcutaneous or Epidural Spinal Stimulation for Enabling Motor Function in Humans With SCI | Mayo Clinic | | - Age ≥ 22 yrs
- Level C1-T10
AIS A, B, C, D- ≥ 1 years
- NOT have a history of frequent, severe, autonomic dysreflexia.
- NOT have history of frequent hypotension or frequent hypertension.
- NOT be ventilator dependent
- have intact spinal reflexes below the level of injury
| Ended | 6 | NA | Technology | Standing/walking/mobility | - 6-Minute Walk Test (6MWT)
- American Spinal Injury Association Impairment Scale (AIS)
- Electromyography
- International Standards for Neurological Classification of Spinal Cord Injury (ISNCSCI)
- Motor evoked potential
- Neurogenic Bladder Symptom Score
- Neurogenic Bowel Dysfunction Score (NBD or NBDS)
- Sensory evoked potentials (including mixed and dermatomal, mSSEPs, dSSEPs, contact heat/laser evoked potentials- CHEPS/LEPs)
- Spinal Cord Injury Spasticity Evaluation Tool (SCI-SET)
| 5 months | 04 March 2022 | 27 October 2021 | 1 | |
