This trial is enrolling 40 participants with chronic, incomplete spinal cord injury to test the effect of arm and leg cycling combined with functional electrical stimulation (FES) and transcutaneous spinal stimulation (tSS) on walking function. FES is a technique that applies electrical stimulation through the skin to nerves to cause contraction of weakened or paralyzed muscles. tSS is a non-invasive technique that uses surface electrodes to deliver electrical stimulation aimed at modifying spinal cord function. If included, participants will be randomly assigned to one of three groups: (1) arm and leg cycling with FES and sham tSS; (2) arm and leg cycling with FES and active tSS; or (3) body weight supported treadmill training. Final testing of walking function will be performed after 6 months.
Traumatic
Non-traumatic
Type
Details
- Participants will be randomly assigned to one of three groups: (1) arm and leg cycling with functional electrical stimulation (FES) and sham transcutaneous spinal stimulation (tSS), (2) arm and leg cycling with FES and active tSS, or (3) body weight supported treadmill training. - FES is a technique that applies electrical stimulation through the skin to nerves to cause contraction of weakened or paralyzed muscles. - tSS is a non-invasive technique that uses surface electrodes to deliver electrical stimulation aimed at modifying spinal cord function. - All participants will complete 60-minute training sessions, three times per week for 12 weeks. - Final testing of walking function will be performed after 6 months.
Main benefits
Standing/walking/mobility
Additional benefits
General health
Spasticity
Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.
Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.
Learn moreWings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.
Learn more