This pilot study is enrolling 20 participants with chronic, incomplete cervical spinal cord injury to test the effect on arm and hand function of cervical epidural spinal stimulation (eSS), alone and paired with transcranial magnetic stimulation (TMS) or structured rehabilitation. eSS is an invasive technique that uses implanted electrodes placed next to the spinal cord to deliver electrical stimulation aimed at modifying spinal cord function. TMS is a non-invasive technique which uses a magnetic field to stimulate the brain. A coil (held over the head) delivers the magnetic stimulation that activates the central nervous system. If included, participants will undergo temporary implantation of electrodes near the cervical spine, followed by a 29-day study involving eSS alone and combined with TMS or structured rehabilitation. Final testing of arm and hand function will be performed after 30 weeks.
Traumatic
Type
Details
- Participants will undergo temporary implantation of electrodes near the cervical spine, followed by a 29-day study involving epidural spinal stimulation (eSS) alone and combined with transcranial magnetic stimulation (TMS) or structured rehabilitation. - eSS is an invasive technique that uses an implanted electrode placed next to the spinal cord to deliver electrical stimulation aimed at modifying spinal cord function. - TMS is a non-invasive technique which uses a magnetic field to stimulate the brain. A coil (held over the head) delivers the magnetic stimulation that activates the central nervous system. - Final testing of arm and hand function will be performed after 30 weeks.
Main benefits
Arm/hand function
Additional benefits
Bladder health/function
Bowel health
General health
Sensory function
Sexual health
Spasticity
Standing/walking/mobility
Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.
Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.
Learn moreWings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.
Learn more