This trial is enrolling at least 12 (up to 21) participants with acute incomplete cervical spinal cord injury to test the safety of repeated NG004 injections (6 injections; 1 every 5 days) into the fluid around the spinal cord. NG004 is an antibody that targets Nogo-A, a protein that inhibits nerve growth. If included, participants will receive one of three different doses of NG004. Final testing of safety and tolerability will be performed after 6 months.
Traumatic
Type
Details
- Participants will receive repeated NG004 injections (6 injections; 1 every 5 days) into the fluid around the spinal cord. - NG004 is an antibody that targets Nogo-A, a protein that inhibits nerve growth. - Final testing of safety and tolerability will be performed after 6 months.
Main benefits
General health
Additional benefits
Arm/hand function
Sensory function
Standing/walking/mobility
Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.
Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.
Learn moreWings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.
Learn more