This trial is enrolling 60 individuals with spinal cord injury to evaluate the effect of different intravenous drugs (remifentanil, esketamine, flurbiprofen) combined with spinal cord stimulation (SCS) on pain and electroencephalogram measurements. SCS is a technique for stimulating the spinal cord to modify spinal cord function. This study requires a surgically implanted stimulator. The electroencephaologram records electrical activity in the brain using scalp electrodes. If included, participants will receive remifentanil, esketamine, or flurbiprofen combined with SCS. Final testing of pain will be performed after 1 week.
Type
Details
- Participants will receive an intravenous drug (remifentanil, esketamine, or flurbiprofen) combined with spinal cord stimulation (SCS). - SCS is a technique for stimulating the spinal cord to modify spinal cord function. The study requires a surgically implanted stimulator. - Final testing of pain will be performed after 1 week.
Main benefits
Pain
Additional benefits
General health
Mental health and psychosocial factors
Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.
Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.
Learn moreWings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.
Learn more