This trial is enrolling 25 individuals with spinal cord injury to test the effect of different stimulation methods on specific muscle groups. If included, participants will undergo either: i) transcranial magnetic stimulation (TMS) to activate the brain; ii) electrical spinal cord stimulation (SCS) to activate the spinal cord; iii) functional electrical stimulation (FES) to activate arms, legs) and trunk; or iv) sham TMS. TMS is a non-invasive technique which uses a magnetic field to stimulate the brain. A coil (held over the head) delivers the magnetic stimulation to activate the central nervous system. SCS is a technique for stimulating the spinal cord via surface electrodes to modify spinal cord function. FES is a technique that applies electrical stimulation through the skin to nerves to cause contraction of weakened or paralyzed muscles. Final testing of muscle activation and response will be performed after 2 months.
Traumatic
Type
Details
- Participants will undergo either i) transcranial magnetic stimulation (TMS) to activate the brain, ii) electrical spinal cord stimulation (SCS) to activate the spinal cord, iii) functional electrical stimulation (FES) to activate the upper limb (arms), lower limb (legs) and trunk (stomach) muscles or iv) sham TMS. - They will attend at least 9 sessions over 2 months, each lasting 2-3 hours. - TMS is a non-invasive technique which uses a magnetic field to stimulate the brain. A coil (held over the head) delivers the magnetic stimulation that activates the central nervous system. - SCS is a technique for stimulating the spinal cord via surface stimulation to modify spinal cord function. - FES is a technique that applies electrical stimulation through the skin to nerves to cause contraction of weakened or paralyzed muscles. - Final testing of muscle activation and response will be performed after 2 months.
Main benefits
General health
Additional benefits
Arm/hand function
Standing/walking/mobility
Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.
Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.
Learn moreWings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.
Learn more