This study is enrolling 228 participants with acute traumatic spinal cord injury to test the effect of different hemodynamic management strategies on general health. Hemodynamic management involves controlling blood flow and blood pressure to ensure that vital organs, including the brain and spinal cord, receive adequate blood supply. If included, participants will receive one of three hemodynamic management strategies during the first 5 days after injury: maintaining a higher blood pressure (85-90 mmHg); ensuring adequate blood flow to the spinal cord (≥65 mmHg); or keeping blood pressure at a normal level (≥65 mmHg). Final testing for motor scores and mobility will be performed after 12 months.
Traumatic
Type
Details
- Participants will receive one of three hemodynamic management strategies: maintaining a higher blood pressure (85-90 mmHg), ensuring adequate blood flow to the spinal cord (≥65 mmHg), or keeping blood pressure at a normal level (≥65 mmHg). - Hemodynamic management involves controlling blood flow and blood pressure to ensure that vital organs, such as the brain and spinal cord, receive adequate blood supply. - Final testing will be performed after 12 months.
Main benefits
General health
Additional benefits
Arm/hand function
Bladder health/function
Bowel health
Sensory function
Standing/walking/mobility
Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.
Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.
Learn moreWings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.
Learn more