This trial is enrolling 200 participants with spinal arachnoiditis and syringomyelia related to spinal cord injury or other infection. The study will compare the effect of two treatment procedures: a Subarachnoid-Subarachnoid (S-S) bypass, which creates a new pathway for cerebrospinal fluid to flow when the natural flow is obstructed; or an intradural adhesion lysis, a surgery that removes or releases scar tissue within the dura mater, the tough outer layer membrane around the cord. Both procedures address symptoms related to abnormal spinal fluid dynamics and spinal cord compression. If included, participants will receive either the S-S bypass or intradural adhesion lysis. Assessment of patient outcomes, complications, and quality of life will be performed after 3-6 months, 12 months and 24 months.
Traumatic
Non-traumatic
Type
Details
- Participants will receive either the Subarachnoid-Subarachnoid (S-S) Bypass or intradural adhesion lysis. - An S-S Bypass is a procedure designed to create a new pathway for cerebrospinal fluid to flow when the natural flow is obstructed. - An intradural adhesion lysis is a surgery aims to remove or release scar tissue within the dura mater, which is the tough outer layer that surrounds the spinal cord. - Following the procedure assessments will be made at 3-6 months, 12 months, and 24 months. - Final assessment of complications and quality of life will be performed after 24 months.
Main benefits
General health
Additional benefits
Arm/hand function
Sensory function
Standing/walking/mobility
Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.
Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.
Learn moreWings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.
Learn more