This pilot study is enrolling 6 individuals with spinal cord injury to test the effect of a novel skin-surface device to deliver neostigmine and glycopyrrolate to improve bowel evacuation. This device allows for the medications to be administered through the skin and into the blood by applying an undetectable electrical current (a process called iontophoresis) rather than using needle injections. If included, participants will receive the 2 medications (neostigmine and glycopyrrolate) transdermally using the wireless ION device during 3 separate sessions. Final testing of bowel health will be performed after 3 days.
Type
Details
- Participants will receive 2 medications (neostigmine and glycopyrrolate) transdermally using the wireless ION device in 3 separate sessions. - This allows for the medication to be administered through the skin and into the circulation of the body by applying an undetectable electrical current rather than intravenously or intramuscularly. - Final testing of bowel evacuation will be performed after 3 days.
Main benefits
Bowel health
Additional benefits
General health
Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.
Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.
Learn moreWings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.
Learn more