This trial is enrolling individuals with chronic spinal cord injury to test the safety and effects of using a short-acting drug (Glyceryl trinitrate) to reduce blood pressure during dangerous blood pressure spikes (autonomic dysreflexia) that can happen during bowel care. If included, participants will receive either: 1) the active drug administered via sublingual spray (0.4 mg) up to three times every 15 minutes; or 2) placebo sublingual spray. Blood pressure testing will be performed during bowel care on two occasions within 28 days, each for up to an hour.
Traumatic
Type
Details
- Participants will either receive 1) the active drug administered via sublingual spray (0.4 mg) up to three times every fifteen minutes or 2) placebo sublingual spray. - Blood pressure testing will be performed during bowel care.
Main benefits
General health
Additional benefits
Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.
Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.
Learn moreWings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.
Learn more