Bowel function following SCI is a high priority for individuals living with SCI. This trial is enrolling individuals with chronic spinal cord injury at the cervical or thoracic level to test the effect of genital nerve stimulation (GNS) on the activity of the anus and rectum, to assess bowel function. If selected, participants will receive GNS applied briefly to determine if they qualify for the study. If qualified, participants will then receive: 1) active electrical stimulation applied to the genital nerve with surface electrodes; and 2) sham stimulation in a random order. Participants will also undergo ano-rectal manometry (ARM) to test anal and rectal function in response to the stimulation.
Traumatic
Type
Details
- One or two study visits (for a total of about 7.5 hours) - In visit 1, participants will receive GNS applied briefly to determine if they qualify for the study. - In visit 2, participants will receive 1) active electrical stimulation applied to the genital nerve with surface electrodes and 2) sham stimulation in a random order. - Ano-rectal manometry (ARM) to test how the anus and rectum are functioning in response to the stimulation
Main benefits
Bowel health
Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.
Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.
Learn moreWings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.
Learn more