About this trial

This is a trial enrolling individuals with chronic cervical spinal cord injuries to test the effect of transcutaneous electrical spinal cord stimulation (TSCS) on upper limb function. TSCS is a technique for stimulating the spinal cord via skin surface electrodes, in this case applied to the skin on the back of the neck. If included, participants will undergo repeated baseline measurements throughout four weeks, followed by intensive exercise therapy for six weeks. Then they will undergo either: 1) continuous TSCS(open-loop); or 2) activity-specific TSCS (closed-loop), followed by a 6-week waiting period without stimulation. Then they will receive the other intervention (closed or open-loop) for another 6 weeks. Each session will last 90 minutes, three sessions per week. Overall participation in the study will last ten months. The trial will include repeated measurements of arm and hand strength, sensation and function. Spasticity will also be assessed.