About this trial

This trial is enrolling individuals with chronic spinal cord injuries to test the effect of a blood flow restriction exercise (BFR) on muscle and vascular function. BFR involves inflating a cuff around the thigh to modify blood flow. Investigators want to see if the exercise improves muscle strength and/or vascular function. If included, one group of participants will undergo an 8-week training period (20 sessions of knee exercises) with BFR. A second group will get 8 weeks, 20 sessions of traditional knee extension/flexion resistance exercise. The two groups will then switch treatments (crossover). A series of measurements will be performed before and after the training periods to assess muscle and vascular function.