This is a trial to test the safety and effect of spinal cord stimulation (SCS) on breathing among individuals with cervical (neck area) spinal cord injuries who need a ventilator to breathe. In this study, stimulation is provided by an electrode implanted next to the spinal cord. If included, participants will first receive respiratory training. Next, participants will receive an implant of the SCS device and 10 days of respiratory rehabilitation using different SCS settings. Stimulation sessions will occur two times per week over 21 months. Final testing, including various measures of breathing function will be performed after 2.5 years.
Traumatic
Type
Details
- assessments before and after respiratory training - surgery for implantation of the stimulation electrodes - 10 days of post-surgery respiratory rehabilitation - 2 times per week stimulation sessions for 21 months - follow-up assessments over 2.5 years
Main benefits
General health
Additional benefits
Mechanism of action
Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.
Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.
Learn moreWings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.
Learn more