This trial is recruiting individuals with chronic paraplegia to test the effect of spinal cord stimulation on standing, stepping, and bladder function. Participants will undergo surgery to implant an electrode array next to the spinal cord (epidural stimulation - scES). Participants will receive either 160 sessions of standing and stepping training (suspended on treadmill) sessions with scES; or 80 sessions of bladder training (capacity and voiding) followed by 80 sessions of standing and stepping training with scES. Both groups will train for 1-1.5 hours, 5 days per week. Independent walking function will be assessed; the investigators also hope to optimize stimulator programming and wireless communication platforms to improve the patient experience.
Traumatic
Type
Details
The participant will receive either: 160 standing and stepping training sessions with epidural stimulation or 80 sessions of bladder training (capacity and voiding) followed by 80 sessions of standing and stepping training with epidural stimulation. Both groups will train for 1-1.5 hours, 5 days per week. Final testing will be performed after the completion of the intervention.
Main benefits
Bladder health/function
Additional benefits
General health
Standing/walking/mobility
Mechanism of action
Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.
Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.
Learn moreWings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.
Learn more