This is a clinical trial enrolling individuals with chronic spinal cord injuries to test combining an implanted device to record brain signal activity (intention to move) and spinal cord stimulation. Spinal cord stimulation is a technique for activating nerve networks to increase spinal cord function. Brain signals for intention to move are recorded on an implanted device (electrocorticogram) directly from the surface of the brain. The brain signals are decoded by computer and then sent to stimulation electrodes implanted on the spinal cord; this will enable voluntary muscle activity (such as leg movement), as intended. The goal is to provide direct communication between a person’s intention to move and the spinal cord. If included in the trial, participants will undergo a surgery to implant the device to measure brain activity, and another surgery to implant a stimulating device on the spinal cord. Additionally, a neurorehabilitation program will be performed. Testing will assess safety, function, and measures of gait performance over the period of 1 year.
Traumatic
Type
Details
Participants are implanted with a (recording) device at the surface of the brain. Participants are implanted with a (stimulating) device at the surface of the spinal cord. The participants will undergo training and rehabilitation. Final testing will be performed at around 1 year. “Training specifications are not provided. Further information needs to be acquired directly from the investigator.”
Main benefits
Standing/walking/mobility
Additional benefits
Arm/hand function
General health
Mental health and psychosocial factors
Sensory function
Spasticity
Mechanism of action
Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.
Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.
Learn moreWings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.
Learn more