This is a trial to test the effect of a technique for stimulating the spinal cord with an implanted electrode placed next to the spinal cord (epidural stimulation) on bladder, bowel, and cardiovascular function after spinal cord injury. If included, participants with prior implantation of the spinal cord epidural stimulation device (Medtronic scES array) will undergo epidural stimulation and have assessments including monitoring of blood pressure and heart rate responses to bladder filling, bowel stimulation during anal pressure measurements, and bowel evacuation for 6 months. Eligible participants who have not had prior implantation of the scES device will have the same blood pressure and heart rate response assessments (without epidural stimulation) for 6 months.
Traumatic
Type
Details
Participants with prior implantation of the scES device will undergo epidural stimulation with assessments including bladder filling, bowel stimulation, blood pressure and heart rate monitoring. Participants without prior implantation of the scES device will undergo the same assessments without stimulation.
Main benefits
Bladder health/function
Additional benefits
Bowel health
General health
Sexual health
Mechanism of action
Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.
Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.
Learn moreWings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.
Learn more