This trial is recruiting individuals with chronic incomplete cervical (neck area) spinal cord injuries to test the effect of remote ischemic conditioning (RIC) during hand exercises. RIC temporarily restricts blood flow by inflating a blood pressure cuff around the arm. This restriction is thought to increase the benefits of the exercises. If included, participants will perform 2 sets of hand exercise, pinching a dynamometer with thumb and index finger at different intensities and durations (10% - 50% of maximal voluntary contraction and durations (2-6 seconds). The exercise will be combined with either 1) the active RIC (5 cycles of 5-minutes inflation and 5-minutes deflation on the non-target arm using higher cuff pressure); or 2) the sham RIC protocol (5 cycles of 5-minutes inflation at lower pressure).
Traumatic
Non-traumatic
Type
Details
The participant will perform 2 sets of hand exercise at different intensities (10% - 50% of maximal voluntary contraction) and durations (2-6s) with either 1) the active RIC ( 5x5 min inflation of 200mmHg cuff pressure) or 2) the sham RIC protocol (5x5min inflation of 10mmHg below the participant’s diastolic blood pressure). Testing will be performed immediately before, immediately after, and 15 minutes after each session.
Main benefits
Arm/hand function
Additional benefits
General health
Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.
Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.
Learn moreWings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.
Learn more