This is a trial to compare the effect of two training types: 1) step training on a treadmill while the body is supported in a harness (Body Weight Support: BWS) alone compared to 2) BWS-assisted step training in combination with another technique for stimulating the spinal cord via the skin surface to modulate spinal cord activity (transspinal stimulation). This study is designed to determine if transspinal stimulation at several frequencies combined with BWS-assisted step training will have more effect on physiological and clinical tests of neurological functioning including walking than BWS-assisted step training alone. If included in this trial, the participant will be randomly assigned to 20 step training sessions of 1) BWS assisted step training alone (control condition), 2) BWS assisted step training with low frequency transspinal stimulation, or 3) BWS assisted step training with high frequency transspinal stimulation. Before and after each session standardized clinical tests will be performed.
Traumatic
Type
Details
- 20 session of step training with 1) BWS assisted step training alone (control condition), 2) BWS assisted step training with low frequency transspinal stimulation, or 3) BWS assisted step training with high frequency transspinal stimulation. - Participants will be randomly assigned to one of the three intervention groups. Participants will be allowed to know their assigned group’s intervention protocol. - Standardized clinical tests will be performed before the intervention and after the 20 sessions are completed.
Main benefits
Standing/walking/mobility
Additional benefits
General health
Sensory function
Spasticity
Mechanism of action
Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.
Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.
Learn moreWings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.
Learn more