This trial is recruiting individuals with chronic spinal cord injuries to test whether spinal cord stimulation improves recovery of blood pressure regulation, voluntary movement, and standing. Participants will have an electrical device (16-electrode epidural array) surgically implanted into the lower back over the spinal cord. Epidural spinal cord stimulation will be combined with a standing device (stand training). Participants will be randomly assigned to one of four groups: epidural stimulation for voluntary leg movement; epidural stimulation for voluntary leg movement combined with stand training; epidural stimulation for cardiovascular function; or epidural stimulation for cardiovascular function with stand training. The main goals are to measure the effect of the stimulation on cardiovascular (blood pressure) and voluntary motor function, and to compare leg movement training only with leg movement training plus stand training. Assessments will also include respiratory, bladder, bowel and sexual function. Quality of life and potential health care costs also will be assessed.
Traumatic
Non-traumatic
Type
Details
Surgery to implant the device into the lower back. The participant will receive 1) scES for voluntary leg movement, 2) scES for voluntary leg movement combined with stand training, 3) scES for cardiovascular function, or 4) scES for cardiovascular function combined with stand training. Testing sessions over 1.5 years. Training specifications are not provided. Further information needs to be acquired directly from the investigator.
Main benefits
General health
Additional benefits
Bladder health/function
Bowel health
Mental health and psychosocial factors
Sexual health
Standing/walking/mobility
Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.
Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.
Learn moreWings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.
Learn more