This is a trial recruiting individuals with chronic complete spinal cord injuries to test the effect of an implanted scaffold combined with stem cells into the injured spinal area. If selected, participants will be randomly assigned to receive either mesenchymal (usually derived from bone marrow, fat, or muscle*) or neural stem cells with the scaffold implant. The scaffold (NeuroRegen™) is a man-made structure intended to mimic the natural tissue environment to support stem cell growth. After surgery, all participants will receive rehabilitation, psychological and nutritional interventions. Outcome assessments will be performed over a 24 month period after surgery. *Note: detailed information about the stem cells, source of cells, need for immune suppression, etc. is not available on clinicaltrials.gov and will need to be provided by the investigator.
Traumatic
Type
Details
Surgery for excision of spinal cord scar and the implantation of the NeuroRegen Scaffold combined with either mesenchymal stem cells or combined with neural stem cells Rehabilitation, psychological and nutritional interventions after surgery Outcome assessments throughout the study duration of 24 months
Main benefits
Arm/hand function
Additional benefits
Bladder health/function
Bowel health
General health
Mental health and psychosocial factors
Sensory function
Standing/walking/mobility
Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.
Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.
Learn moreWings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.
Learn more