This trial is enrolling individuals with new spinal cord injuries to the cervical (neck) area to test a drug, Glyburide. This drug is approved for use in other diseases, e.g., diabetes type 2. Researchers want to see if the drug is safe and whether it has a protective effect on the nervous system. This trial will also measure effect of this drug on improving neurological recovery. This is an open-label study — all participants will receive the drug and there is no control (comparison) group. Participants will receive the drug (by mouth) within 8 hours of injury, for 3 days. Follow up will occur at days 28, 42, 84, 182 and 365.
Traumatic
Type
Details
Admission at the study site to take the drug within 8 hours of injury. Taking the drug by mouth every 6 hours for 3 days. Starting on admission into the study, study testing and/or data collection will be done until discharge and on Days 14, 28, 42, 84, 182, and 365.
Main benefits
General health
Additional benefits
Arm/hand function
Sensory function
Standing/walking/mobility
Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.
Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.
Learn moreWings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.
Learn more