This trial is recruiting individuals with spinal cord injuries to study the safety and effect of cell transplantation as a treatment. Schwann cells harvested from the sural nerve (located in the lower leg) of each participant will be transplanted into the center of the participant's spinal cord injury. Researchers want to see if these cells promote functional recovery by repairing myelin (insulation) on spinal cord nerves. Potential recovery will be enhanced by fitness and rehabilitation activities before and after transplantation. If selected, participants will undergo surgery to collect the cells and place them into the spinal cord. Enrollment will target 2 participant groups, thoracic level and cervical level. Safety and functional assessments will be done after transplantation at weeks 1 and 2 and months 2 and 6.
Traumatic
Type
Details
At the University of Miami (prior and post surgery), participants will receive fitness conditioning and rehabilitation in order to maintain health and promote neuronal activity and potential neuroplasticity within the central nervous system. Monitoring throughout 6 months post-surgery.
Main benefits
Standing/walking/mobility
Additional benefits
Arm/hand function
Bladder health/function
Bowel health
General health
Pain
Sensory function
Sexual health
Spasticity
Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.
Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.
Learn moreWings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.
Learn more