This is a trial to study the cerebrospinal fluid (CSF) surrounding the spinal cord of individuals with acute spinal cord injuries. The trial will find out how well the spinal cord is being supplied with blood and to find molecular indicators (markers) in the CSF that may predict nervous system recovery after SCI. The study will also look at how blood pressure drugs (vasopressors) influence spinal fluid pressure. Trial participants will have a thin, temporary tube (catheter) inserted into their lower back to access spinal cord fluid 3 times per day, for 5 days. A neurological exam will follow 3, 6, and 12 months after injury.
Traumatic
Type
Details
A thin tube will be inserted into the lower back for 5 days from which CSF will be taken out every 8 hours, 3 times per day. Neurological examinations after 3, 6, and 12 months after the injury. The participant will receive specific drugs against low blood pressure (NORepinephrine and/or DOPamine) after their injury and will switch between these drugs at specific time-frames.
Main benefits
General health
Additional benefits
Pain
Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.
Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.
Learn moreWings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.
Learn more